The concept of regional resilience is one of the prominent concepts of the recent approach to resilience that has been emphasized by various researchers to deal with various regional crises, including flood risk crises. However, despite the research that has been conducted, there has not been the necessary coherence and continuity in identifying the components of regional resilience. On the other hand, in the various categories presented, the ranking and priority between the components of regional resilience have not been determined in general. The present study has reviewed the research conducted with the aim of identifying the components of regional resilience and achieving a reliable model. Therefore, to answer the questions 1. What are the main components related to regional resilience? and 2. Which of the components of regional resilience is most effective in dealing with floods? the meta-composition analysis method has been used. Thus, in the first stage, relevant articles were selected and validated between the period 2015 and 2023; Then, using various coding methods, regional resilience indicators were identified and categorized. This categorization was based on three principles of researchers’ theoretical knowledge, expert opinion, and an overlapping approach. The results showed that six economic, social, cultural resources, geography, physical infrastructure, and resilience components were identified as the main components of regional resilience in the face of flood risk. Also, in order to rank and determine the priority among the identified components, DEMATEL analysis and ISM interpretive structural complementary analysis were used. The results of these analyses showed that the economic component, as an independent variable with a higher level of influence, had a greater impact on other elements of the system in the face of floods. Also, in the analysis of intermediary (connective) components, the resilience component was ranked first. Given that the two components of economy and resilience have had a higher level of impact as independent and mediating components, respectively, it is necessary to emphasize economic resilience as the first priority of regional resilience programs to accelerate regional resilience programs and, as a result, provide greater capacities to deal with flood risk.