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The main purpose of the present study was to determining the relationship between organizational culture and organizational entrepreneurship in physical education head quarters of Tehran province, which was carried out by a descriptive field method. The study population was the experts and heads of physical education headquarters of Tehran province. Statistical sample set of entire the experts and heads of physical education head quarters of Tehran province (n=102). In order to collect information demographic questionnaires, Denison organizational culture Questionnaire (=&alpha0/955) organizational entrepreneurship Questionnaire (=&alpha0/953) were used. Descriptive methods were used to analyze the data and in order to normality of data a Kolmogorov- Simonov and to determine the relationship a Pearson correlation coefficient were used. Data analysis results showed that there is a significant relationship between the organizational culture and organizational entrepreneurship (r=0/331, p<0/05). Also organizational culture has a positive and significant relationship (p<0.05) with indices of organizational entrepreneurship: structure(r=0.333), strategy (r=0.43), management patronage (r=0.271) and persuasion-encouragement system(r=0.256), but there is not relationship between organizational culture and construction and information system (p>0/05).