Volume 21, Issue 26 (12-2023)
RSMT 2023, 21(26): 129-140 |
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Kharazmi University , vahid7fazeli@yahoo.com
Abstract: (3799 Views)
Objective: The aim of the present study was to investigate the effect of combined exercise on aortic atherosclerosis and FGF23 in male rats with chronic renal failure. Methods: In this study, 20 male Wistar rats (mean weight 10 ± 250 g) were induced by NX5 / 6 method for chronic renal failure. After 2 weeks of recovery, they were randomly divided into two groups of control (n= 10) and combined training (n= 10) and performed a combined training protocol for 8 weeks. The combined training protocol consisted of two resistance training exercises on a ladder with 2 sets and 6 repetitions with percentages of body weight and aerobic exercise included 30 minutes of low-intensity treadmill activity. Results: The results showed that combined exercise reduced aortic atherosclerosis and decreased plaques, and FGF23 decreased significantly (p = 0.001). Parathoromon hormone also significantly decreased (p = 0.041) and calcium and phosphorus significantly decreased (p = 0.004 and p = 0.005, respectively). Conclusion: Overall, the results showed that combined training could decrease FGF23, parathoromon hormone, calcium and phosphor on aortic atherosclerosis and cardiovascular disease indices in chronic renal failure patients.
Type of Study: Research |
Received: 2023/04/6 | Accepted: 2023/11/25 | Published: 2023/12/31
Received: 2023/04/6 | Accepted: 2023/11/25 | Published: 2023/12/31
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