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R Shiri, H Nikbakht, M Gholami, Kh Ebrahim,
Volume 18, Issue 19 (7-2020)

Time under Tension of muscle is one of the variables of strength training that contributes to its adaptation. The present study was conducted the effects of six weeks of resistance training with the varying Time under Tension of muscle on VEGF and endosotene serum levels  in healthy young women. This study was conducted on 20 female students (22.65±2.03years) Subjects were randomly and equally assigned to two groups with a Time under Tension of 1s- 1s(Normal Speed Contraction) and 3s- 3s (slow Speed Contraction). The exercise load was the same in both groups and resistance training was done in a circular manner for six weeks, three days a week in eight stations. Blood samples were taken from the subjects to study  research variables before the training period and 48h after the last session of the training. Data were analyzed by covariance analysis at a significant level of P≤0.05. There was no significant difference between the serum levels of VEGF and endostein in both groups (P≥0.05). In the strength test, the  SSC group experienced increase power further. However, there was no difference between the two groups in indicators related to angiogenesis for six weeks and  most probably, for this indicator needed more training time, but  practice with more Time under Tension (3s- 3s) can lead to increase power further.

Dr Shirin Yazdani, Prof Nader Farahpour,
Volume 19, Issue 21 (9-2021)

 Background and Objective: although it is documented that the spine and hip alignments alter in scoliosis subjects, but the effect of these changes on the lower extremities’ biomechanics have not been well understood yet. So, the aim of this study was to compare hip, knee and ankle joint’s power generation and absorption during gait in patients with adolescent idiopathic scoliosis (AIS) and healthy controls.  Methods: Using motion analysis system with 4 Vicon-460 cameras and two Kistler force plates, the kinematics and kinetics of gait was assessed in twenty girls with AIS and 20 matched healthy controls, then the power of the right and left hip, knee and ankle joints in sagittal plane was calculated. Data was analyzed using ANOVA statistical method with significance level of α<0.05. Results: Results showed that in scoliosis group, the peak power absorption of the right knee was significantly 12.5% smaller than that in control group (p=0.01). But, peak power generation and absorption of the hip and ankle joints in both right and left limbs were not statistically differed between the two groups (p>0.05). Conclusion: scoliosis is associated with the smaller power absorption of the knee joint at convex side. This might be linked with unilateral alterations of the joints' moment, joint forces, and the related muscle activity which might impose asymmetrical force to the hip and cause curve progression.
Fadideh Alabaf Yousefi, Roghayeh Pouzesh Jadidi, Jabbar Bashiri, , Javad Vakili,
Volume 19, Issue 22 (12-2021)

Background and Objective: the aim was to investigate the effects of 12 weeks of High Intensity Interval Training (HIIT) and curcumin supplementation on expression levels of FSTL1 and Smad7 and also Type I, III and IV collagens in rat model with myocardial infraction (MI). Methodology: 48 male rats were randomized into five groups of Reference, HIIT, Curcumin, Concomitant (HIIT+ Curcumin) and Control, following isoproterenol induced myocardial infarction. After Reference group execution in order to conform the MI, curcumin was administrated through oral gavage 15 mg/ HIIT sessions were conducted for five days per week, each session for 60 minutes, consisted of 10 bouts (each for 4 min) of running repetitions at 85-90% of v VO2 peak separated by 2 min active rest intervals between running periods. Left ventricular FSTL1, Smad7 and also type I, III and IV collagens expression level was detected by western blotting. Results: In all three intervention groups of HIIT, Curcumin and Concomitant, the cardiac weight was significantly higher (p=0.001, p=0.018 and p=0.001 respectively), while type IV collagen expression level was significantly lower (p=0.001 in any circumstances) than Control group. However, only in the Concomitant group, a significantly lower type III collagen (p=0.033) expression level as well as higher FSTL1 (P=0.001) and Smad7 (P=0.008) expressions were recorded, compared to the Control group. Conclusion: A diminished cardiac type IV collagen expression level in accompany with a zero mortality rate in all three interventions could likely imply on the safety of HIIT as well as curcumin supplementation to suppress post infraction myocardial fibrosis. However, only concomitant intervention could decrease infracted left ventricular type III collagen expression level, with an elevated FSTL1 and Smad7 expressions, which outlines their synergistic prescription to achieve better results. However, more researches remains to be done because of the lack of evidence and study limitations.

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