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Showing 5 results for Ayati

Maryam Khayati, Manijeh Pakravan, Ali Sonboli,
Volume 3, Issue 2 (9-2016)

Tripleurospermum transcaucasicum (Manden.) Pobed (Asteraceae, Anthemideae) is newly recorded from East Azarbayejan Provice, NW Iran. It is morphologically similar to T. caucasicum (Willd.) Hayek and T. monticolum (Boiss. & A.Huet) Bornm. The morphological and anatomical diagnostic characters of new record are compared with closely related species. The geographical distribution of new records and related species in Iran are presented.

Sakineh Kaboli Kafshgiri , Kazem Parivar, Javad Baharara, Nasim Hayati Roodbari, Mohammad Amin Kerachian,
Volume 3, Issue 4 (3-2017)

Chemical pesticides possess toxic and destructive impacts on the reproductive system and disrupt endocrine function. In this experimental study, the effect of movento, as a chemical pesticide, was investigated in comparison with chitosan, a biological pesticide, on the female reproductive system in vivo. In this study, 56 mice were randomly dived into 7 groups including control and experimental groups treated with movento and chitosan. After a 21-day treatment, mice were killed and their ovaries and blood being collected. In addition, the samples were fixed and stained with H & E method. The results exhibited that treatment with 2.5 and 5 mg/kg chitosan had no significant effect on the number and diameter of primary, secondary and antral follicles, while these items were significantly reduced in 10 mg/kg ch-itosan group and all movento-treated groups as well. In addition, the level of sexual hormones, such as estradiol, FSH and LH, was decreased in 10 mg/kg chitosan group and all movento-treated groups in comparison with the control gr-oup. The findings showed that movento affected the sexual hormone levels, ovary and ovarian follicle structure and in-duced abnormality in female reproductive system, while chitosan, as a biological pesticide, should be used due to its minimum effects on female reproductive system

Havva Sharifdini, Kazem Parivar, Nasim Hayati Rodbari,
Volume 4, Issue 3 (12-2017)

Of different types of bio-compatible nano‌particles, iron oxide nanoparticle has attracted attention for its applications especially in medicine and magnetic resonance imaging (MRI). We decided to study histological changes in testis and spermatogenesis in mature male mice that are affected by ironoxide nanoparticles (Fe2O3) during fetal period. In this study, the mice were divided into three experimental and two control and sham groups. Iron oxide at do-ses of 10, 30, 50 mg/kg were injected into pregnant mice during 10th, 12th and 14th days of the critical period of fetus testis development. After the maturation of the mice which were born, slices with the thickness of 0.06 µm were prep-ared from adult male testis and epididymis, stained with hematoxylin and eosin. The cells were counted, then the obta-ined data was analyzed with one-way ANONA and Tukey testes. The results showed that the number of epididymis sp-erms at the doses of 10 and 30 mg/kg, testis weight at the dose of 30 mg/kg, primary spermatocytes at the dose 10mg/kg had increased, while the testis diameter in all the three experimental groups and the volume of the testis at the dose of 50 mg/kg had decreased. Disorganization and vacuolization were observed at high doses. Passing through the cell me-mbrane, and considering its oxidation and reduction potentials, it was observed that Iron oxide nanoparticle acts as anti-oxidant at low doses and shows toxicity at high doses. The fact obtained in the paper reflects the dual potential of the ir-on oxide nanoparticle.
Sasan Ghobadian, Hossein Ganjidoust, Bita Ayati, Neda Soltani,
Volume 5, Issue 1 (6-2018)

Special properties and various applications of Spirulina species have led to the growing focus of biotechnology to the cost effective cultivation. Open ponds used in the most commercial cultivation have many deficiencies such as risk of contamination, lack of light penetration, inefficient mixing and low productivity. In this study, an innovative reactor was designed and manufactured. By adding a control area, it was possible to control some environmental conditions for a limited amount of open pond volume. The conventional pumping system was replaced by a new elevator system to reduce the damage of to the fragile cells. The baffles structure and aeration from bottom, contributed to better mixing system. The effect of tree factors (Circulation Cycle (Cir. Cyc.), Control Volume (Con.Vol.) and Irradiance Intensity (Irr. Int.) in units of hours, percentage and Lux respectively) on the quantity of biomass (Specific Growth Rate (SGR, day-1) and fifth and seventh day dry weight (g/L)) were evaluated using RSM-CCD. The maximum biomass dry weight (0.915 g/L) was achieved in longest circulation cycle (12 hours), 30% Con. Vol. and 7000 Lux light intensity. The optimal irradiance intensity to achieve the highest biomass was 8700 Lux. According to the results, due to the great influence of Con. Vol. and Cir. Cyc., it is possible to increase the productivity and enhance the culture dry weight by controlling a limited amount of ponds volume (20%), subject to economic considerations. These successful results can provide the context using a control zone for several open ponds to improve the overall efficiency.

Mojtaba Cheravi, Javad Baharara, Parichehreh Yaghmaei, Nasim Hayati Roudbari,
Volume 8, Issue 4 (1-2022)

Nowadays, researchers have made extensive efforts to find new treatments for nerve damage. Meanwhile, the role of exosomes in cell-cell communication is considered to be a new mechanism. Exosomes can act as suitable differentiating agents. The aim of this study was to investigate the differentiating effect of cerebrospinal fluid-derived exosomes on adipose mesenchymal stem cells in alginate hydrogel. Exosomes were extracted from the cerebrospinal fluid by ultracentrifugation and were then identified by atomic force microscopy (AFM), SEM and DLS technique. In addition, Adipose Mesenchymal Stem cells in alginate hydrogel were treated with different concentrations of exosomes. Cell survival was assessed by MTT and Acridine Orange/Ethidium Bromide methods. Cell differentiation was processed by immunocytochemistry and Real-Time PCR. Examinations confirmed the presence of exosomes with an approximate size of 70 nm. Cell survival results indicate that he ability of cells to survive and proliferate during 14 days. Also, the expression of MAP2 proteins (microtubule-associated protein 2) and Nestin (intermediate filament protein) was confirmed by immunocytochemistry. The results of Real Time - PCR showed that during the seventh and fourteenth days the expression level of MAP2 gene increased and the expression of Nestin gene showed a significant decrease compared to the control group. This study showed that exosomes extracted from cerebrospinal fluid can cause neuronal differentiation of Adipose mesenchymal stem cells in alginate hydrogel scaffolds.

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