Search published articles

Showing 2 results for Kerachian

Sakineh Kaboli Kafshgiri , Kazem Parivar, Javad Baharara, Nasim Hayati Roodbari, Mohammad Amin Kerachian,
Volume 3, Issue 4 (3-2017)

Chemical pesticides possess toxic and destructive impacts on the reproductive system and disrupt endocrine function. In this experimental study, the effect of movento, as a chemical pesticide, was investigated in comparison with chitosan, a biological pesticide, on the female reproductive system in vivo. In this study, 56 mice were randomly dived into 7 groups including control and experimental groups treated with movento and chitosan. After a 21-day treatment, mice were killed and their ovaries and blood being collected. In addition, the samples were fixed and stained with H & E method. The results exhibited that treatment with 2.5 and 5 mg/kg chitosan had no significant effect on the number and diameter of primary, secondary and antral follicles, while these items were significantly reduced in 10 mg/kg ch-itosan group and all movento-treated groups as well. In addition, the level of sexual hormones, such as estradiol, FSH and LH, was decreased in 10 mg/kg chitosan group and all movento-treated groups in comparison with the control gr-oup. The findings showed that movento affected the sexual hormone levels, ovary and ovarian follicle structure and in-duced abnormality in female reproductive system, while chitosan, as a biological pesticide, should be used due to its minimum effects on female reproductive system

Azita Mehrbakhsh, Javad Baharara, Saeedeh Zafar Balanejad, Mohammad Amin Kerachian,
Volume 7, Issue 3 (11-2020)

Electromagnetic waves (EMF) are a mixture of electrical and magnetic waves. The energy transmitted by these radiations is absorbed by living tissues. Electromagnetic fields seem to cause infertility in women. Cannabis is annual herbaceous plant grows in tropical areas. This study was conducted to investigate the protective effects of hydroalcoholic extract of Cannabis sativa in various doses of 50, 100 and 150 mg / kg on the damages induced by electromagnetic fields of 50 Hz and 50 Gauss, on the puberty of ovarian follicles and levels of FSH, LH, estradiol and progesterone hormones in NMRI immature mice. In this study, 48 NMRI immature female mice with an approximate age of 16 days and approximate weight of 18 grams were divided into 8 (experimental, sham, positive control and negative control) groups. After the treatment, the ovaries were extracted and weighed, and sections with H& E staining, the number of primordial, primary, secondary, and atretic follicles were counted, and the level of hormones have been done. The results showed that the concentration of 50 mg / kg of cannabis extract after the exposure to electromagnetic field of 50 Gauss could increase the number of follicles and reduce the number of atresia follicles. The group treated with the concentration of 50 mg / kg of cannabis extract after the exposure to electromagnetic field of 50 Gauss showed increased levels of FSH, LH and estradiol hormones (p <0.01) and a reduced level of progesterone (p <0.01). Therefore, the concentration of 50 mg / kg of cannabis extract have a protective role in preventing infertility due to ovarian tissue damages induced by electromagnetic fields.

Page 1 from 1     

Creative Commons Licence
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2023 CC BY-NC 4.0 | Nova Biologica Reperta

Designed & Developed by : Yektaweb