TY - JOUR JF - nbr JO - NBR VL - 8 IS - 4 PY - 2022 Y1 - 2022/1/01 TI - Evaluation of phytochemical characterizations and antifungal potency of aqueous and methanolic extracts of Tulipa biflora TT - ارزیابی خواص فیتوشیمیایی و پتانسیل ضدقارچی عصاره‌های آبی و متانولی لاله هفت رنگ N2 - The purpose of this study was to evaluate phytochemical characterizations and the in vitro antifungal capacity of the aqueous and methanolic extracts of the flower of Tulipa biflora Pall., against various yeast and mold species. For this purpose, fresh flowers were grinded and then macerated in methanol and water overnight, the resulted extracts were then evaluated by various tests. The results indicated that the extracts had different phytochemical components such as terpenoids, tannins, flavonoids, alkaloids, phenols, and phlobatannins. After the evaporation of solvents, antifungal activities of the concentrated extracts were evaluated by the well-diffusion method on Candida albicans, Trichosporon asahii, Yarrowia lipolytica, Aspergilus niger and Fusarium oxysporum. The results showed that the extracts were effective on yeasts and mold species studied except for Aspergilus niger. In order to determine the minimum inhibitory concentration (MIC) and minimum biocidal concentration (MBC) of the extracts, anti-microbial tests were performed in micro-plates. The methanolic extract had more antifungal effectsthan that in the aqueous extract. Therefore, the extract of Tulipa biflora could be introduced as a source for antifungal agents. SP - 297 EP - 306 AU - Tafakori, Vida AD - Department of Cell and Molecular Sciences, Faculty of Biological Sciences, Kharazmi University, Tehran. Iran KW - alkaloid KW - fungicides KW - MBC KW - MIC KW - phenol UR - http://nbr.khu.ac.ir/article-1-3475-en.html DO - 10.52547/nbr.8.4.297 ER -