Volume 10, Issue 3 (2-2010)                   2010, 10(3): 879-890 | Back to browse issues page

XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Designation and construction of a plasmid containing gp96 and Her2 and in vitro expression using GFP gene. Journal title 2010; 10 (3) :879-890
URL: http://jsci.khu.ac.ir/article-1-1438-en.html
Abstract:   (4834 Views)
Abstract
Objective: DNA vaccinations using Her2 gene have shown some success in immunotherapy of Her2-expressing tumors, but the potency needs to be greatly enhanced. Heat Shock Proteins (HSPs) have shown to be potent adjuvant in immunotherapy of tumors and affect different aspects of innate and adaptive immune responses. We utilized the adjuvant effect of gp96 and attempted to gain two aims, firstly, production of a construct containing fusion of Her2 and gp96, and secondly, investigation of gene expression in the construct using green fluorescent protein (GFP) gene.
Keywords: Fusion, Her2, gp96, GFP
Full-Text [PDF 1270 kb]   (1404 Downloads)    
Type of Study: S | Subject: Science
Published: 2010/02/15

Add your comments about this article : Your username or Email:
CAPTCHA

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Quarterly Journal of Science Kharazmi University

Designed & Developed by : Yektaweb