Research in Sport Medicine and Technology

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The aim of this study was to investigate the effect of 8-weeks of resistance training and vitamin D supplementation on some indicators of renal function in male rats with renal failure. Methods: In this experimental study, 16 male rats (7-8 weeks and mean weight: 350 to 370 gr) were divided into four groups (n = 4): training, supplement, training and supplement and control group. After induction of kidney damage through NX 5.6 surgical method and two weeks later, resistance training was performed for 8 weeks. Simultaneously, 1000 unit of vitamin D per week intramuscularly was injected. Finally, glomerular purification (using urea and creatinine levels) and serum levels of vitamin D, calcium and phosphorus were measured. Descriptive statistics, one-way ANOVA test and Tukey post hoc test were used to analyze the data. The results showed that glomerular filtration and vitamin D in the training and supplementation groups showed a significant increase compared to the control and training groups (P<0.05). However, Urea and creatinine and serum calcium and phosphorus significantly was decreased (P<0.05). It seems that the simultaneous use of resistance training and vitamin D supplementation can affect glomerular filtration rate.

Keywords: Resistance training, Vitamin D, Glomerular purification, renal failure

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