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Mojtaba Salehpour, Faezeh Rezvani, Farzane Hatami,
Volume 0, Issue 0 (11-2019)

Background: GDNF protein is involved in neurocognitive plasticity and sarcopenia, and the increase of GDNF due to resistance training leads to healthier aging and delays sarcopenia, and TRX resistance training improves the performance and morale of the elderly. The purpose of this research is the effect of six weeks of TRX training on the level of GDNF protein in the serum of elderly women.
Materials and methods: The purpose of the research is applied with a semi-experimental method including pre-test - post-test with control group and field and laboratory data. 28 elderly women aged 55 to 75 years old from the retirement center of Shahid Rajaee Tarbiat University of Tehran were randomly assigned to two experimental groups (15 people) with an average age of 60.86 ± 5.60, weight 75.00 ± 11.95, BMI ± 4.22 27.65 and six weeks of TRX training and the control group (13 people) with an average age of 64.38 ± 4.03, weight 72.69 ± 4.95, BMI 28.33 ± 2.18 and no training were divided. In the first and sixth weeks, both groups were tested for upper body strength, lower body strength and GDNF protein level by ELISA method.Shapiro-Wilk test was used to check the normality of data distribution, Levine's test for homogeneity of variances and one-way analysis of covariance test at a significance level of P < 0.05 was used to test hypotheses and statistical calculations were performed with spss24.
Results: In the results of covariance analysis of upper body and lower body strength, there is a significant difference between the two groups at the level of P <0.05. By removing the effect of the pre-test variable, there is a significant difference between the amount of GDNF protein in the experimental and control groups. By comparing the adjusted averages in the experimental and control groups, the amount of GDNF protein in the experimental group (443.102 ± 15.751) is significantly higher than the control group (209.756 ± 17.029) (P < 0.05).
Conclusion: Six weeks of TRX training had a significant effect on the amount of GDNF protein, upper and lower body strength of elderly women, and it can probably be effective in reducing or delaying sarcopenia.
V Saleh, H Sadeghi, P Shams Najafabadi, M.r Rezaeian, H Valizadeh,
Volume 15, Issue 13 (9-2017)

The aim of this study was to compare the profile of anthropometric, somatotype and body composition between novice and professional 6 to 8 years old gymnasts. A total of 40 gymnasts in tow group (20 novice gymnasts and 20 professional gymnasts) participated in this study. A total of 17 anthropometric, somatotype and body composition variables were recorded of each subject. The tools used in this study are: questionnaires (individual information and general health evaluation), chronometer, band meter, and movable weight scale, stadiometer, sliding calliper and somatotype software. In ferential and descriptive statistics and independent T test were used to analyze the obtained data. The level of significance was 0.05. There were significant differences in skinfold percentage (triceps, Supraspinatus and calf), total hand length, hip and calf, circumferences, BMI, endomorph and ectomorph between tow group) p<0.05). From an anthropometric stand point, 6 to 8 years old is a lowest and best age for select and talent identification. According to the results, between two groups, professional gymnasts exhibited lower BMI, circumferences (hip and calf), skinfolds, endomorphy and more total hand length, mesomorphy and ectomorphy than nivice gymnasts. On average, professional and novice gymnasts were in ectomorph-mesomorph and endomorph-mesomorph status respectively.

Mohadse Salehi Sarbizhan, Amir Letafatkar, Mehdi Khaleghi,
Volume 16, Issue 16 (12-2018)

The most common side effect of physical activity is the risk of musculoskeletal damage, that anterior cruciate ligament injury is the most common one. Purpose of the study is comparing the effect of six weeks of comprehensive injury prevention training on anterior cruciate ligament with internal and external feedback on the proprioception and knee function of active female university students. Forty five active female university students aged 18-25 years were volunteered and randomly assigned to three groups (internal, external and control) and they performed the protocol three times a week for six weeks. Proprioception and function of the knee joint were measured using goniometer and functional tests in two stages  namely pre-test and post-test. Statistical analysis of covariance, paired t test and Tukey's post hoc tests were used for statistical analysis with a significant level of p≤0.05. Overall results of the study showed that the present exercise protocol with internal and external feedback had a significant effect on the proprioception of p≤0.001 and p=0.000 for the knee performance and there was no significant difference between the two training groups. Regarding the results of the study, it is suggested that the present training protocol be addressed by coaches and sport sciences specialists as a complementary tool and method, along with other training methods, for those who are prone to damage to the anterior cruciate ligament.

Dr Ali Barzegari, Dr Saeid Naghibi, Samaneh Safayi, Dr Mohammadhasan Dashti Khovidaki, Dr Anahita Salehi,
Volume 20, Issue 24 (3-2023)

The purpose of this study was to compare two methods of aerobic exercise on the levels of SOD and TNF-α in the heart tissue of diabetic rats. 40 male Wistar rats aged ten weeks were randomly divided into four groups of 10: healthy control, diabetes, diabetes+MIT and diabetes+HIT. The moderate intensity training group ran 5 sessions per week for 8 weeks on the treadmill for 60 minutes at a speed of 25 meters per minute, and the high intensity training group also 5 sessions per week for 8 weeks with a training time of 60 minutes and at a speed of 34 meters per minute. The heart tissue of rats was examined to determine the amount of changes in SOD and TNF-α using ELISA method. To investigate the difference between groups of variables, one-way analysis of variance and Tukey's post hoc statistical tests were used at the significance level of P≥0.05. The results showed that there was a significant difference in the levels of TNF-α and SOD in the heart tissue of rats among the four research groups (P≤0.001). The levels of TNF-α in the HIT training group also showed a significant decrease compared to the diabetic group (P=0.001), While these changes in the MIT exercise group compared to the diabetes group was a non-significant decrease (P=0.117), the amount of SOD levels between the MIT and HIT exercise groups also showed a significant increase compared to the diabetic group (P=0.001). It seems, aerobic exercise with different intensities can improve SOD and TNF-α levels. Although the intensity of exercise in periodic exercise has been an effective factor in changing the values of both variables.

Mojtaba Salehpour, Ali Sarlak, Hadi Samadi,
Volume 21, Issue 26 (12-2023)

Introduction: The increase of iron due to aging affects the process of ferroptosis, and the final product of lipid peroxidation, MDA, is the central regulator of ferroptosis. Therefore, the aim of the research was to determine the effect of eight weeks of endurance training on the expression of GPX4 and MDA in the soleus muscle of aged male rats.
Materials and Methods: This study is of an experimental type. 20 healthy rats were divided into two groups of 10 each: training group and control group. The training was done incrementally for eight weeks. 48 hours after the last training session, the soleus muscle of mice was surgically removed and the amount of variables was measured by gene expression and ELISA methods.
Results: There was no significant difference in the level of GPX4 gene expression in the soleus muscle of exercise group rats compared to control group rats (p=0.4079). But the amount of MDA in the training group was significantly reduced compared to the control group (p=0.0028).
Conclusion: According to the findings of the present research, it seems that the effect of endurance training in this research shows a decrease in ferroptosis. The absence of a significant difference in the level of GPX4 gene expression is a sign that endurance training with this intensity does not affect it.

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