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Showing 7 results for Interval Training

Dr Fatemeh Kazeminasab, Miss Motahareh Mohebinejad, Dr Karim Azali Alamdari,
Volume 0, Issue 0 (11-2019)

Background and purpose: Excessive fat deposition is associated with cardiovascular diseases, diabetes as well as hypertension. The aim of this study was to determine the net effect size of high intensity interval training (HIIT) on some factors associated with insulin sensitivity in adults with overweight and obesity.
Materials and methods:  A search for English articles was conducted in Web of Science, Scopus, and PubMed databases without limiting the year of publication until February 2023. To calculate the effect size, WMD and 95% confidence interval were calculated using random effect model. Fixed effect model meta regression was used to determine treatment effects associations with other variables.
Results: In total, 13 studies with 446 adults with overweight and obesity (149 females, and 317 males) with 24.7-57 years old were included in the present meta-analysis. The results showed that HIIT caused a significant decrease in fasting glucose [WMD=-8.65 mg/dL, P=0.002], fasting insulin [WMD=-1.88 U/L P=0.005], and diastolic blood pressure (DBP) [WMD=-3.33 mmHg. Weak correlations were observed in between HIIT’s net effect on DBP and insulin (r=-0.32, p=0.019) as well as with subjects’ age (r=-0.29, p=0.037) respectively in meta-regression assessments.
Conclusion: The rate of DBP reduction is sharper and these changes are also correlated with age. Therefore, HIIT is suggested as a Non-pharmacological Approach to prevent against future cardiometabolic risk factors in this population.
Mr Aidin Zarifi, Dr Hamid Rajabi, Dr Sadegh Hasan Nia, Dr Mohamadreza Dehkhoda, Dr Babak Mirsoltani,
Volume 13, Issue 10 (10-2015)

High-intensity interval training (HIT) induces skeletal muscle metabolic and performance adaptations that
resemble traditional endurance training despite a low total exercise volume. On the other hand, fatty acid
oxidation is increases in skeletal muscle with endurance training. This process is regulated in several sites,
including the transport of fatty acids across the plasma membrane. The transportation across this membrane is
recognized to be primarily protein mediated. Therefore, the purpose of this study was to determine the effect of
low-volume high intensity interval training on protein content of sarcolemmal fatty acids transporters (FAT/CD36
and FABPpm) in young men. Twenty recreationally active young men were assigned to a HIT (n=10, 19.3 yr old,
67.2 kg body wt, and 172.7 cm ht) or Control (n=10, 19.7 yr old, 65.9 kg body wt, and 174.4 cm ht) group. HIT
group performed three training sessions per week over 4 weeks. Each session consisted of 8-11×60 s intervals
at ∼100% of peak power output elicited during a ramp VO2peak test separated by 75 s of recovery. Skeletal
muscle (vastus lateralis) biopsy samples were obtained before and after training. HIT increased (17.5%)VO2peak (p<0.05). Also, after 4 weeks low-volume HIT, sarcolemmal content of CD36 and FABPpm increased
14 and 25 percent ,respectively (p<0.05). Therefore, the results showed that the practical model of low-volume
HIT could increase aerobic capacity and sarcolemmal content of CD36 and FABPpm. The increase indicates
that the facilitation of in muscle fatty acid transportation can be adapted which in turn increases the fat oxidation

Akram Arzani, Shadmehr Mirdar,
Volume 16, Issue 16 (12-2018)

The aquaporin5 (AQP5) is an integral membrane protein that plays an important role in maintaining water homeostasis in the lung during of puberty. The purpose of this study was to evaluate the effect of period of reduced training with Nigella Sativa (NS) supplementation on AQP5 levels in the lung of Male Wistar rats during of puberty. 110 newborn three-week old male Wistar rats with average weight of 68±9 gr, were randomly divided into three groups included; the base, control and training groups. After a 6-week training period, the control group was divided into 2 groups with and without NS and training groups were divided into 6 groups including frequency, volume and intensity taper with and without NS. After 6 weeks, NS supplements were fed daily by gavages to groups of NS 500 mg/kg body weight. Progressive interval training was performed in 6 sessions, 30 minutes each session at a speed of 15 to70 meters per minute, Then, taper phase for three weeks in decreasing pattern, intensity, frequency and volume were performed. AQP5 levels were measured by ELISA methods. Analyzed is done with two-way ANOVA and LSD test at α≤0.05. While NS supplementation were increase average AQP5 levels in the taper groups of frequency, volume and intensity, But, there were no significant differences (P≥0/45) between AQP5 levels in with and without NS groups. Furthermore, three-week taper versus two weeks taper a significant increase the average AQP5 levels in the groups of with and without NS. It is suggested that the antihistaminic and antinociceptive effects of the NS with a period of reduced training with increasing levels of AQP5 would improve the physiological and functional parameters of the lung during of puberty.

A.r Kazem, A.r Haghpanah, A.b Dakhili,
Volume 17, Issue 18 (12-2019)

Muscle atrophy is one of the consequences of aging and sports activities may prevent it. The aim of this study was to evaluate the effect of high intensity interval training on gene expression of Tweak and Fn14 in EDL muscle of aged C57bl/6 mice. For this purpose, 28 male C57bl/6 mice aged (n=14) and adult (n=14) were assigned in two groups of training (n=7) and control (n=7). After one-week familiarization, training groups participate in 4 weeks high intensity training program on treadmill, with an intensity of 85% of the maximum speed in the first week up to 95% of the maximum speed in the last week, in 2-minute intervals (6 in the first week to 10 in the last week) with 1 minute rest between intervals. 48 hours after the last training session, the mice were sacrificed. Then gene expressions of Tweak and Fn14 in EDL muscle were measured. The findings show that aging has significant effect on EDL muscle weight (P=0.032).  Also the results showed that with increasing age Tweak and Fn14 mRNA expression increased in the EDL muscle (P=0.001 and P=0.002 respectivly). On the other hand, training can reduce Tweak and Fn14 gene expression in both old and adult groups (P=0.001). On the other hand, although training slightly increased EDL muscle weight in both adult (P=0.117) and old (P=0.321) groups, this value statistically was not significant. Thus, aging is associated with an increase in Tweak and Fn14 mRNA expression, which could possibly be involved in muscle weight changes associated with aging. Since that high intensity interval training decrease these mRNA expression, can might be utilized HIIT for maintenance aging and adult of muscle mass.
E Fasihi Ramandi, N Khaledi,
Volume 18, Issue 19 (7-2020)

Diabetes is a common metabolic disease. In diabetic patients glucose uptake is reduced and FGF-21 plays an important role in glucose uptake, alsoTNF-α is an inflammatory factor that increases in diabetes. The purpose of this study was to investigate the effect of 6 weeks of HIIT training on the gene expression FGF-21 in the liver and the serum TNF-α level of male diabetic rats. For this purpose, 48 Wistar rats were randomly divided into four groups Control, diabetes, high intensity interval training, and diabetes and high intensity interval training. For the induction of diabetes, peritoneal injection (Streptozotocin 50 mg/kg) was used. Training protocol including 10 set of 1-minute running (between each set of 2 minutes of rest) 3 sessions per week and was completed within 6 weeks. Finally, after the extraction of liver samples, the expression of the FGF-21 gene was measured by Real Time PCR and serum TNF-α level with ELISA kit.There was no significant change in expression of FGF-21 in any group, but the reduction of serum levels of inflammatory factors, such as TNF-α protein at the level of significance (p=0.05), and maintaining and improving the time to exhaustion, was shown by high intensity interval training (0.000).Likely the inflammatory factors of diabetes such as TNF-α have a deleterious effect on the expression and binding of FGF-21 (β-Klotho) cofactors And causes resistance to FGF-21 into various tissues of the body, such as the liver. Exercise can reduce inflammation caused by diabetes.

H Rajabi, P Motamedi, D Zabihi,
Volume 18, Issue 19 (7-2020)

The purpos of this study was to determine the effect of  twelve session of high intensity cycle training with blood flow restriction on aerobic and anaerobic performance of active student men. To this purpose, 24 valentear active students men from physical eduction faculty of kharazmi university aged 19-23 years old, students (mean ± SD weight: 67.89±6 kg, height: 173.92±5.41cm, and  BMI: 22.7±6.84kg/m2) divided into three groups of blood flow restriction (BFR) (n=8), none blood flow restriction(NBFR) (n=8) and control group (n=8). The exercise consisted of cycling at 80% Wmax for ten 1-min bouts, with a 2-min rest between bouts with 50% Wmax (total time, 30 min). Before and after implementation of the training protocol, Astrand Test to check the aerobic  performance and Wingate test to check anaerobic performance was conducted. To data analysis, the independent t-test, analysis of variance test and post hoc test (LSD) was used. Results indicated that two weeks of high intensity cycling with and without blood flow restriction does have a significant impact on VO2max(p=0.000) and Wmax(p=0.000) and time to exhaustion (p=0.001). The results indicate a further increase in aerobic performance components, in exercise with blood flow restriction training group compared to the unrestricted blood flow training group. The results olso indicated that tow weeks of cycle training with occlusion does not have a significant impact on peak anaerobic power(p=0.064), average anaerobic power(p=0.058) and minimum anaerobic power(p=0.826). In general, the results showed a partial restriction of blood during cycling interval training have affect on aerobic adaptations, but  does not affect on anaerobic adaptations.

Reza Sabzevari Rad, Hekmat Ehsan Bakhsh, Ebrahim Fasihi Ramandi,
Volume 19, Issue 22 (12-2021)

Adiponectin plays an important role in many metabolic and heart diseases. Regulation of liver enzymes is also essential for the health of the body's organs. Therefore, this study aimed to evaluate the effect of a HIIT training period on adiponectin levels and serum concentrations of liver enzymes in obese and overweight boys. 22 obese and overweight boys were selected and randomly divided into two groups of control and experimental. The experimental group performed eight weeks of HIIT pedaling with 80% HR reserve intensity for 3 days a week. The variables of adiponectin, aspartate aminotransferase (AST), alkaline phosphatase (ALP), alanine aminotransferase (ALT) using kits and laboratory methods as well as aerobic power, body mass index, and fat percentage of tests in the two stages before and after Exercise protocol was also measured and covariance test was used to compare the research variables and Pearson correlation coefficient was used to examine the relationship. The results were analyzed at a significant level (P<0.05) using SPSS software version 24. Performing eight weeks of HIIT exercise using a bicycle resulted in a non-significant reduction in adiponectin (P>0.05), AST(P>0.05)   and ALP(P >0.05) enzymes. This exercise also significantly reduced ALT enzyme (P<0.05) and fat percentage (P<0.05) and increased aerobic capacity (P<0.05)
HIIT exercise strengthens aerobic power and reduces the percentage of fat and reduces the liver enzyme ALT in obese boys. Of course, more research is needed to clarify this issue.

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