Volume 13, Issue 10 (10-2015)
RSMT 2015, 13(10): 91-101 |
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Khademi S, Ranjbar R, Ghanbarzadeh M. Effect of 8 weeks of circuit training on serum Irisin levels and Insulin Resistance Index in overweight girls. RSMT 2015; 13 (10) :91-101
URL: http://jsmt.khu.ac.ir/article-1-151-en.html
URL: http://jsmt.khu.ac.ir/article-1-151-en.html
Abstract: (7766 Views)
The purpose of this study was the effect of eight weeks of circuit training on the Irisin levels and
the Insulin Resistance Index (HOMA-IR) in overweight women. Materials and Methods: In this study 22
overweight women voluntarily were chosen (Age 26.04±4.43 yrs, BMI 29.35±2.53 kg/m2) and were divided
to two groups of control (n=11) and experimental (n=11). In the experimental group, subjects performed
circuit training for eight weeks and four times per week. Blood sample was taken before and 48 hours after
the last training session. Statistical analysis at the level of P<0.05 was done. Findings: After eight weeks of
training, the level of Irisin in experimental group significantly increased while the HOMA-IR had a
significant reduction (p<0.05). Also Pearson correlation co-efficiency test shows that there is a reverse
relationship between irisin and HOMA-IR (P≤0.05). Conclusion: It appears that circuit training improves
body composition and metabolic disorders such as insulin resistance through Irisin induction in overweight
women.
Type of Study: Research |
Received: 2017/01/21 | Accepted: 2017/01/21 | Published: 2017/01/21
Received: 2017/01/21 | Accepted: 2017/01/21 | Published: 2017/01/21
References
1. Finucane, M.M., Stevens, G.A., Cowan, M.J., Danaei, G., Lin, J.K., Paciorek, C.J. (2011). National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9•1 million participants. Lancet. 377: 557-67.
2. Pradhan, A.D., Skerrett, P.J., Manson, J.E. (2002). Obesity, diabetes, and coronary risk in women. Journal of Cardiovascular Risk. 9(6): 323-30.
3. Hee Park, K., Zaichenko, L., Brinkoetter, M., Thakkar, B., Sahin-Efe, A., Joung, E., Mantzoros, C.S. (2013). Circulating irisin in relation to insulin resistance and the metabolic syndrome. The Journal of Clinical Endocrinology & Metabolism. 98(12): 4899-4907.
4. Boström, P., Wu, J., Jedrychowski, M.P., Korde, A., Ye, L., Lo, J.C. Spiegelman, B.M. (2012). A PGC1-[agr]-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature. 481(7382): 463-8.
5. Joung, K.E., Park, K.H., Zaichenko, L., Sahin-Efe, A., Thakkar, B., Brinkoetter, M., Mantzoros, C.S. (2014). Early life adversity is associated with elevated levels of circulating leptin, irisin, and decreased levels of adiponectin in midlife adults. The Journal of Clinical Endocrinology & Metabolism. 99(6): E1055-E60.
6. vanMarkenLichtenbelt, W.D., Vanhommerig, J.W., Smulders, N.M., Drossaerts, J.M., Kemerink, G.J., Bouvy, N.D., Teule, G.J. (2009). Cold activated brown adipose tissue in healthy men. New England Journal of Medicine. 360(15): 1500-8.
7. Moreno-Navarrete, J.M., Ortega, F., Serrano, M., Guerra, E., Pardo, G., Tinahones, F.,Fernández-Real, J.M. (2013). Irisin is expressed and produced by human muscle and adipose tissue in association with obesity and insulin resistance. The Journal of Clinical Endocrinology & Metabolism. 98(4): E769 E78.
8. Aydin, S. (2014). Three new players in energy regulation: Preptin, adropin and irisin. Peptides. 56: 94-110.
9. Huh, J.Y., Dincer, F., Mesfum, E., Mantzoros, C.S. (2014). Irisin stimulates muscle growth-related genes and regulates adipocyte differentiation and metabolism in humans. International Journal of Obesity. 38(12): 1538-44.
10. Choi, Y.K., Kim, M.K., Bae, K.H., Seo, H.A., Jeong, J.Y., Lee, W.K., Park, K.G. (2013). Serum irisin levels in new-onset type 2 diabetes. Diabetes Research and Clinical Practice. 100(1): 96-101.
11. Boström, P.A., Fernández-Real, J.M., Mantzoros, C. (2014). Irisin in humans: recent advances and questions for future research. Metabolism: clinical and experimental. 63(2): 178-80.
12. Miyamoto-Mikami, E., Sato, K., Kurihara, T., Hasegawa, N., Fujie, S., Fujita, S., Iemitsu, M. (2015). Endurance Training-Induced Increase in Circulating Irisin Levels Is Associated with Reduction of Abdominal Visceral Fat in Middle-Aged and Older Adults. PloS one. 10(3).
13. Blüher, S., Panagiotou, G., Petroff, D., Markert, J., Wagner, A., Klemm, T., Mantzoros, C.S. (2014). Effects of a 1-year exercise and lifestyle intervention on irisin, adipokines, and inflammatory markers in obese childrenObesity. 22(7): 1701-8.
14. Pekkala, S., Wiklund, P.K., Hulmi, J.J., Ahtiainen, J.P., Horttanainen, M., Pöllänen, E., Mäkelä, K.A, Kainulainen, H., Häkkinen, K., Nyman, K., Alén, M., Herzig, K.H., Cheng, S. (2013). Are skeletal muscle FNDC5 gene expression and irisin release regulated by exercise and related to health? The Journal of Physiology. 591(21): 5393-5400.
15. Huh, J.Y., Panagiotou, G., Mougios, V., Brinkoetter, M., Vamvini, M.T., Schneider, B.E., Mantzoros, C.S. (2012). FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise. Metabolism. 61(12): 1725-38.
16. Norheim, F., Langleite, T.M., Hjorth, M., Holen, T., Kielland, A., Stadheim, H.K., Drevon, C.A. (2014). The effects of acute and chronic exercise on PGC-1α, irisin and browning of subcutaneous adipose tissue in humans. FEBS Journal. 281(3): 739-49.
17. Ferrannini, E. (1998). Relationship between impaired glucose tolerance, non-insulin dependent diabetes mellitus and obesity. European Journal of Clinical Investigation. 28(suppl 2): 3–6.
18. Solomon, T.P., Sistrun, S.N., Krishnan, R.K., Del Aguila, L.F., Marchetti, C.M., O'Carroll, S.M., Kirwan, J.P. (2008). Exercise and diet enhance fat oxidation and reduce insulin resistance in older obese adults. Journal of Applied Physiology. 104(5): 1313-19.
19. Sanchis-Gomar, F., Perez-Quilis, C. (2014). The p38–PGC-1α–irisin–betatrophin axis: Exploring new pathways in insulin resistance. Adipocyte. 3(1): 67-8.
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